It's made use of as an analgesic (ache reliever) found in medications on your own or together with other medicinal elements for instance acetaminophen or acetylsalicylic acid.
Lung Complications. Promethazine/phenylephrine/codeine really should not be utilized When you've got serious asthma, problems breathing, or other lung issues. Promethazine/phenylephrine/codeine could make these problems worse.
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The presence of the polymorphism in CYP2D6 ends in non-performing enzyme variant and will be related to reduced drug mtabolism or reduced therapeutic reaction when handled with codeine.
Respiratory Melancholy in Youngsters The mix of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric sufferers under six yrs of age.
Acceptable research done to date have not demonstrated geriatric-precise difficulties that may Restrict the usefulness of promethazine and codeine mix during the aged.
Codeine: In patients receiving MAO inhibitors, an Preliminary tiny check dose is highly recommended to permit observation of any too much narcotic effects or MAOI interaction.
If one will not be readily available, it is possible to mix medication with dirt, coffee grounds, or cat litter, then location the combination inside a sealed plastic bag and toss the bag in the trash.
LOOKING FOR A Medication? — See this listing of medicines that contain codeine to determine more details on a particular medication.
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Narcotic analgesics bring about histamine release, which appears to become chargeable for wheals or urticaria at times viewed at the internet site of injection on parenteral administration.
Promethazine is contraindicated in comatose states, and in click here persons recognised to become hypersensitive or to own experienced an idiosyncratic reaction to promethazine or to other phenothiazines.
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